【摘要】 为得到较高通量的手性选择性阴离子交换膜,将β环糊精作为手性选择剂添加在膜相中,制得具有手性选择性的阴离子交换膜。将其用于拆分DL-对羟基苯甘氨酸外消旋混合物的电渗析过程。在碱性条件下L-对羟基苯甘氨酸优先通过手性阴膜,分离因子达1.25,通量达到60.4 g.m-2.h-1,验证了预期的拆分效果。使用普通阴膜,并在电渗析实验中对比了在料液中添加β环糊精以及不添加β环糊精的分离性能,β环糊精添加在料液中有明显的拆分效果,不添加β环糊精的普通电渗析几乎没有拆分效果。结果进一步验证了手性选择性来源于手性膜的β环糊精。更多还原

【Abstract】 Chiral selective anion-exchange membranes were prepared with β-cyclodextrin as the chiral selector to develop a new chiral selective membrane with a high enantiomer separation flux. The membranes were then used in the electrodialysis resolution process to separate DL-4-hydroxyphenylglycine racemic mixture. The results show that L-4-hydroxyphenylglycine is preferentially transported through the chiral selective anion-exchange membrane with basic conditions. The maximum selection factor is (1.25 with a flux of (60.4 g·m⁽-2·h^-1. For comparison, conventional electrodialysis experiments with β-cyclodextrin in the feed had a selection factor of 0.28 and without β-cyclodextrin the selection factor was about 1. These experiments show that β-cyclodextrin in the chiral selective membrane is the cause of the selectivity.更多还原