【摘要】 目的:对急性卒中后抑郁进行评价,并探讨早期心理干预治疗的效果。方法:选择180例首发急性卒中患者作为研究对象,用Hamilton抑郁量表、抑郁自评量表和社会支持量表进行评价,并进行logistic多元逐步回归分析。患有抑郁的110例患者随机分为心理干预组和对照组,两组均接受药物治疗,心理干预组同步进行心理干预。结果:卒中后抑郁的发生率为61.11%;病灶位于皮质和皮质前部的患者抑郁评分显著高于病灶位于皮质下和后部的患者;心理干预组抑郁明显改善,治愈率和有效率分别为69.09%和94.55%显著高于对照的40%和60%。结论:首发急性卒中的抑郁发生率约为2/3,其严重程度与病变部位有关,在药物治疗的同时进行心理干预的效果较好。更多还原

【Abstract】 Objective: To evaluate poststroke depression and the effect of early psychological intervention. Methods: A total of 180 patients with initial acute stroke were recruited in the study. They were evaluated with Hamilton Rating Scale for Depression, Self-Rating Depression Scale, and Social Support Rating Scale and were analyzed with multiple logistic stepwise regression. One hundred ten patients with depression were randomly divided into two groups: the psychological intervention group and the control group. Both groups were treated with medicines at the same time; the psychological intervention group received psychological intervention simultaneously. Results: The incidence of depression was 61.11%. The depression score in patients whose lesions located in cortices and in the anterior cortices were significantly higher than those whose lesions located in subcortices and in the posterior cortices. The patients’ depression improved significantly by psychological intervention. The cure rate and effective rate in the psychological intervention group were 69.09% and 94.55%, respectively. The cure rate and effective rate in the control group were 40% and 60%, respectively. There was significant difference between the two groups.Conclusions: The incidence of depression is about 2/3 in patients with initial acute stroke. Its severity is associated with the position of lesion. There will be a better outcome if it is treated with pharmaceutical therapy and with psychological intervention as an adjunctive therapy.更多还原