【摘要】 目的:分析评价应用导管介入技术治疗子宫肌瘤和宫颈癌的临床疗效。方法:选择19例子宫肌瘤、13例宫颈癌皆经一侧股动脉入路,行两侧子宫动脉插管,对肌瘤者分别选择KMG、PVA微球或碘化油+平阳霉素乳剂,栓塞阻断其血供;宫颈癌者应用明胶海绵颗粒+抗癌药物行手术前灌注栓塞辅助治疗。结果:19例子宫肌瘤、13例宫颈癌共64支子宫动脉均插管成功并栓塞,同时对宫颈癌行双侧髂内动脉和子宫动脉抗癌药物灌注,19例子宫肌瘤经3~12个月随访,平均瘤体缩小率59.4%,多发者中的部分小肌瘤消失,1例坏死脱落,临床症状明显改善;13例宫颈癌介入治疗3周后手术切除顺利,标本组织学示癌巢趋向消失,周边组织有淋巴细胞浸润,部分宫颈恢复正常,其中2例癌组织消失,本组32例介入治疗后皆无严重并发症发生。结论:介入治疗子宫肌瘤安全、微创且疗效肯定;对宫颈癌术前介入可有效提高手术切除率和降低复发率,值得临床广泛应用。更多还原

【Abstract】 Objective:To analyze and evaluate the clinical efficacy of catheter intervention in treating hysteromyoma and cervical cancer.Methods:19 cases of hysteromyoma and 13 cases of cervical cancer were selected and applyed bilateral uterine arterial intubation,with KMG,PVA particles or lipiodol-PYM emulsion in hysteromyoma and gelatin spongia granula combined with anticancer drugs in cervical cancer.Results:The intulation and embolism in total 64 uterine arteries was successful,and anticancer drugs were infused in bilateral internal iliac arteries and uterine arteries in cervical cancer.Followed up 3 months to 12 months,the average diminished rate of hysteromyoma was 59.4%.Some small tumors disappeared in cases with multiple hysteromyoma and shedded in 1 case.Clinical symptoms obviously improved.The operation in 13 cases of cervical cancer performed successfully at 3 weeks after interventional therapy.Their histological specimens showed disappearing cancer tissue,with peripheral infiltrating lymphocytes.The cervix in some cases recovered to normal including 2 cases with disappedred cancer tissue.There was no serious complications in all 32 cases after interventional therapy.Conclusion:The interventional therapy for hysteromyoma is safe,minitrauma and effective.Preoperative interventional therapy for cervical cancer can effectively improve the rate of surgical excision and decrease recurrence rate.It should be recommended.更多还原