【摘要】 目的:观察江苏宜兴地区中小学生的常年性变应原致敏状况。方法:2002￣2003年以宜兴市丁山镇930名中小学生(6～16岁)为对象进行室尘和尘螨变应原皮肤划痕试验。结果:室尘和尘螨变应原的皮试阳性率分别为13.1%和10.0%,总阳性率为17.5%。CochranArmitage趋势分析表明,变应原致敏率随年龄增长而上升(P<0.005);小学一、四年级与初中一年级各组间变应原致敏率无统计学差异,而高中一年级学生的致敏率明显高于其他各年级组(P<0.005)。结论:宜兴地区中小学生对常年性变应原的致敏随年龄呈增加趋势,尤以高中学生的致敏率上升为著,应加强环境干预。更多还原

【Abstract】 Objective: To investigate the prevalence of atopic sensitization to perennial allergens among schoolchildren in Yixing City, Jiangsu Province. Methods: Between 2002 and 2003, skin scratch tests (SST) by using house dust (HD) and D. farinae (Df) allergen extracts were carried on 930 students of primary, middle and high schools (6-16 years old) in Dingshan Town, Yixing City. Results: The positive rate of SST was 13.1% for HD, 10.0% for Df, and 17.5% for total. A significant trend of increasing atopic sensitization was observed among age-group (P < 0.005). The prevalence did not show obvious difference among primary and middle students, but was significantly higher in high school students (P < 0.005). Conclusion: These results suggest a remarkable increase of sensitization to perennial allergens among high school students in the study area. Environmental prevention should be paid much attention to in this period.更多还原