【摘要】 细胞免疫在抗病毒感染中发挥着至关重要的作用。人类免疫缺陷病毒(HIV)感染所引起的细胞免疫反应是由CD8+T淋巴细胞的亚群细胞毒性T细胞(CTL)介导的先天免疫。CTLs一方面通过细胞毒性作用杀伤感染的细胞,另一方面分泌可溶性抗病毒因子(CAF)发挥直接的抗病毒作用,因此成为HIV感染中细胞免疫的重要组成部分。本文就HIV感染这一疾病过程中CD8+T淋巴细胞所发挥的非细胞毒性抗病毒效应作一概述。更多还原

【Abstract】 Cellular immunity plays a crucial role in antiviral infections. The cellular immune response caused by human immunodeficiency virus (HIV) infection is mediated by cytotoxic T lymphocytes (CTLs) and belongs to innate immunity. As important components of cellular immunity in HIV infection, CTLs kill infected cells by cytotoxic function as well as secretion of solubility antivirus factors (CAF). This review summarized so far as the noncytotoxic antiviral efficiency of CD8+ T lymphocytes.更多还原