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青银注射液中总绿原酸的紫外含量测定
DETERMINATION OF THE CONTENT OF TOTAL CHLOROGENIC ACID IN QING YING INJECTION BY ULTRAVIOLET SPECTROPHOTOMETRY
【摘要】 目的测定青银注射液中总绿原酸的含量。方法采用紫外分光光度法在324nm处测定吸收度,并用绿原酸的吸收系数计算其含量。结果青银注射液中总绿原酸的平均含量为19.38mg/ml。结论该法操作简便快速,稳定性,精密度,重现性和回收率均较好,可用于青银注射液生产过程中的质量控制。
【Abstract】 Objective: To determine the content of total chlorogenic acid in Qingying injection. Methods: Ultraviolet spectrophotometry was employed to determine the absorbance at wavelength 324nm. Then the content was calculated by absorption coefficient of chlorogenic acid. Results: The average content of total chlorogenic acid is 19.38 mg/ml. Conclusion: This method is simple, rapid, and stable, with good precision,reproducibility, and recovery. It can be used for quality control in production process of Qingying injection.
【关键词】 青银注射液;
总绿原酸;
分光光度法;
含量测定;
【Key words】 Qingying Injection; Total chlorogenic acid; Ultraviolet spectrophotometry; Content determination;
【Key words】 Qingying Injection; Total chlorogenic acid; Ultraviolet spectrophotometry; Content determination;
【基金】 “九五”国家科技攻关项目(96-901-05-020)
- 【文献出处】 泸州医学院学报 ,Journal of Luzhou Medical College , 编辑部邮箱 ,2005年06期
- 【分类号】R286.0
- 【被引频次】5
- 【下载频次】255