【摘要】 目的对复发性外阴阴道念珠菌病(RVVC)的致病危险因素进行统计和治疗探讨。方法对性病门诊的60例RVVC患者,配对选择VVC患者作为对照,进行危险因素条件logistic回归统计分析;另外把RVVC患者随机分为三组,分别用伊曲康唑、氟康唑、特比奈芬间断治疗6个月,比较其治疗效果。结果性病门诊中RVVC的危险因素包括性伴感染传播、滥用抗生素、口服避孕药致内分泌改变及抗真菌药物使用不当均为RVVC的发生危险因素;用伊曲康唑和氟康唑治疗RVVC,效果要优于用特比奈芬。结论治疗RVVC要注意消除或控制其危险因素;选择伊曲康唑或氟康唑进行每月间断抗真菌治疗有明显效果。更多还原

【Abstract】 Objective:To investigate the risk factors of recurrent vulvovaginal candidiasis(RVVC)and the efficacy of there different kinds of antifungal therapy.Methods:60 patients with RVVC in our STD clinic were matched 60 patients with VVC to investigate the risk factors. The difference in risk factors among the three groups was analysed by conditional logistic regression, and the 60 patients with RVVC were divided randomly into three groups,and were treated with itraconmazole,fluconaxole and terbinafine for 6 months. Results:The results showed that,in STDs clinic,antibiotic abuse ,contraceptives,sexual transmission of infected partner and the non-C.albicans species were the risk factors for RVVC.The efficacy of itraconazle,fluconazole are better than terbinafine in treatment of RVVC.Conclusion:To pvevent the recunent of RVVC,it is important to preclude the risk factors,and itraconazole fluconazole for 6 months treatment were showed good efficacy in RVVC.更多还原