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尿胰蛋白酶原-2在急腹症中筛选急性胰腺炎的价值

Role of Urinary Trypsinogen-2 in Screening for Acute Pancreatitis in Patients with Acute Abdomen

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【作者】 王彤李莉符岳常建星姜骏吴海东杨鹰

【Author】 WANG Tong, LI Li, FU Yue, CHANG Jian,xing, JIANG,Jun, WU Hai,dong, YANG Ying Department of Emergency, The Second Affiliated Hospital of Sun Yat,sen University, Guangzhou, 510120

【机构】 中山大学附属第二医院急诊科中山大学附属第二医院急诊科 510120510120510120

【摘要】 目的:探讨尿胰蛋白酶原鄄2测定在急腹症中筛选急性胰腺炎的价值。方法:对68例因腹痛就诊的病人,在检测血、尿淀粉酶的同时做尿胰蛋白酶原鄄2测定及B超检查。结果:24例经B超及血、尿淀粉酶等联合确诊为急性胰腺炎中有22例尿胰蛋白酶原鄄2阳性,敏感性为91.7%,另44例非胰腺炎的腹痛病人有2例假阳性,特异性为95.5%,其敏感性和特异性均较血、尿淀粉酶为优,24例急性胰腺炎中B超发现有胆嚢结石胆嚢炎者9例。结论:尿胰蛋白酶原鄄2测定是急诊科急腹症筛查和诊断急性胰腺炎的良好检验指标。

【Abstract】 Objective: To evaluate the values of urinary trypsinogen,2 test in screening for acute pancreatitis in patients with acute abdomen. Methods:The levels of urinary trypsinogen,2 and serum and urinary amylases were assayed as well as ultrasonography in 68 patients with acute abdomen. Results: 24 patients were diagnosed as acute pancreatitis. Of which, 22 were positive to urinary trypsinogen,2 and the sensitivity was 92.3%. Five cases with false positive were found in 44 non,pancreatitis patients and the specificity was 95.7%. Urinary trypsinogen,2 test was more sensitive and specific than serum and urinary amylases test in diagnosing acute pancreatitis. Of 24 acute pancreatitis patients, 9 were found with cholecystitis and cholelithiasis. Conclusion: Urinary trypsinogen,2 test is a good marker in screening and diagnosing acute pancreatitis in patients with acute abdomen.

  • 【文献出处】 岭南急诊医学杂志 ,Lingnan Journal of Emergency Medicine , 编辑部邮箱 ,2005年02期
  • 【分类号】R657.5
  • 【被引频次】2
  • 【下载频次】47
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