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类风湿关节炎免疫吸附剂载体——碳化树脂的制备及性能研究
PREPARATION AND PROPERTIES OF DNA CARBONIZED RESIN AS ADSORBENT FOR REMOVAL OF RHEUMATOID FACTOR
【摘要】 以苯乙烯、丙烯腈为单体,二乙烯苯为交联剂,添加一定量的致孔剂,在水相中采用分步聚合工艺制成高分子树脂,再经高温碳化制备碳化树脂。研究结果表明,单体交联度为35%时,碳化树脂比表面积达到601m2/g。用该碳化树脂包埋DNA后对类风湿因子IgG、IgM、IgA的吸附清除率达到了52.9%、58.5%、37.0%。
【Abstract】 In this paper,we discussed about a novel method for the preparation of a carbonized resin which used styrene and acrylonitrile as monomers,divinylbenzene as a cross-linker.The polymerized resin then carbonized at high temperature.Experimental results indicate that the best degree of crosslinking is 35% while the surface area per gram of carbonized resin was 601m2/g.The adsorbent preparated by immobilizing DNA on carbonized resin is applied to adsorb rheumatoid factor from blood,the adsorption capacity for IgGRF,IgMRF,IgARF are 52.9%,58.5%,37.0% respectively.
【Key words】 Immunoadsorbent; Carbonized resin; Styrene; Acrylonitrile; Divinylbenzene; Rheumatoid factor.;
- 【文献出处】 离子交换与吸附 ,Ion Exchange and Adsorption , 编辑部邮箱 ,2005年06期
- 【分类号】TQ460.6
- 【被引频次】1
- 【下载频次】259