儿童动脉导管未闭Amplatzer封堵器封堵前后左心功能的变化

【摘要】 目的了解动脉导管未闭(PDA)患儿封堵前后左心功能变化。方法12例患儿均采用Amplatzer封堵器封堵动脉导管未闭,运用超声心动图在术前3d以及术后3d对12例患儿左心功能[(包括左室舒张末期内径(LVEDD)、收缩末期内径(LVESD)、左室舒张末期容积(LVEDV)、收缩末期容积(LVESV)、每搏搏出量(LVSV)、射血分数(LVEF)和短轴缩短率(LVFS))]进行检测,将封堵前后测量数据分别用统计学配对t检验。结果LVEDD,LVEDV,LVESV,LVSV封堵前分别由(49.5±7.6)mm,(116.3±33.7)mL,(33.6±12.9)mL,(88.9±34.5)mL;封堵后3d降为(40.2±5.2)mm,(67.8±33.8)mL,(26.3±11.4)mL,(52.5±28.0)mL(P<0.05);LVEF,LVFS封堵前分别为(70.8±8.9)%,(36.8±5.8)%;封堵后5d分别为(72.5±9.8)%,(35.6±7.9)%(P>0.05),LVEF和LVFS变化不大。结论应用Amplatzer封堵器治疗儿童PDA是一种有效的方法,能改善PDA患者的左心功能。更多还原

【Abstract】 Objective To study the change of left cardiac function be fore and after patent ductus arteriosus(PDA) occluded with Amplatzer Septal Occl uder (ASO). Methods 12 PDA children were occluded with ASO. 12 cases’ left cardiac function were measured with ultrasonic cardiogram at pre operative 3 d and postoperative 3d , which including LVEDD, LVESD, LVEDV, LVESV , LVSV, LVEF and LVFS. Results The level of LVEDD,LVEDV,LVE SV,LVSV at preoperative were decreased from (49.5±7.6)mm, (116.3±33.7)mL, (33. 6±12.9)mL, (88.9±34.5)mL to (40.2±5.2)mm, (67.8±33.8)mL,(26.3±11.4)mL, (52. 5±28.0)mL at postoperative 3d respectively (P<0.05) . There were no signifi cant difference for LVEF and LVFS (P>0.05), which the level of LVEF and LVFS was (70.8±8.9%), (36.8±5.8%) at preoperative and (72.5±9.8%),(35.6±7.9%) at postoperative respectively. Conclusion It can improve left cardiac function of PDA children to treat PDA with ASO更多还原