【摘要】 目的:通过分析比较临床晚期卵巢上皮癌患者,经初次接受肿瘤细胞减灭术,肿瘤切净者、基本切净者与未 切净者的5年生存率,探讨肿瘤细胞减灭术残余肿瘤的大小对其预后的影响,以及术后的治疗与预后。方法:自1991年1月 至1998年5月,共收治临床晚期卵巢上皮癌62例,回顾性分析其术后的治疗及预后,并对其结果进行讨论。结果:21例肿瘤 切净者其5年生存率为47.6%,35例肿瘤基本切净的5年生存率为22.6%。35例肿瘤基本切净者中,12例残余肿瘤≥1cm 和23例≤2cm的5年生存率分别为41.7%和39.1%。基本切净者中,22例术后1年内化疗<6个周期的5年生存率为 23.1%。结论:从上述资料分析说明,残余肿瘤体积愈小,可减少耐药性产生,提高化疗效果及5年生存率。肿瘤切净者的 年生存率高于肿瘤基本切净者的5年生存率。应重视化疗的规范化,合理选择多途径治疗。术后1年内化疗≥6～8周期可 提高基本切净者的5年生存率及患者的生活质量。更多还原

【Abstract】 Objective:To analyze the difference of 5-year survival rate of stage Ⅲ epidermic ovarian cancer between total resection and partly resection of debulky operation.Methods:From January 1991 to May 1998,62 epidermic ovarian cancer patients on stage Ⅲ accepted debulky operation and the post-operation treatment method.Their prognosis and results were discussed.Results:The 5-year survival rate of 21 total resection and partly resection were 47.6% and 22.6% respectively.In the partly resection group,there were 12 patients whose tumor mass were ≥1cm and 23 patients whose tumor mass were≤2cm,and the 5-year survival rate were 41.7% and 39.1% respectively.22 patients received chemotherapy and their 5-year survival rate were 23.1%.Conclusion:The residual size was related to drug resistance,chemotherapy effect and 5-year survival rate.The 5-year survival rate of total resection was higher than that of partly resection.We should pay attention to standardize chemotherapy and combined chemotherapy.更多还原