【摘要】 目的:探讨曲美他嗪对扩张型心肌病(DCM)心力衰竭(CHF)的临床疗效。方法:40例扩张型心肌病伴中、重度心力衰竭患者。随机分为常规治疗组(对照组)和曲美他嗪治疗组(治疗组),观察曲美他嗪治疗前及治疗8周后,对心功能分级、LVEF值及LVDd的影响。结果:曲美他嗪治疗组临床心功能分级明显改善、LVEF值显著提高、LVDd显著减小,而血压、心率则无影响。结论:曲美他嗪能明显改善扩张型心肌病患者的心功能,值得推广应用。更多还原

【Abstract】 Objective: To evaluate the clinical therapeutic effect of trimetazidine on dilated cardiomyopathy(DCM) accompanied by moderate to severe congestive heart failure(CHF). Methods:40 patients with DCM accompanied by moderate to severe congestive heart failure were randomized into routine treated group and trimetazidine treated g;roup( therapeutic group), and their grades of heart function, left ventricular ejection fraction( LVEF) and left ventricular end-distolic diameter before and after treatment with trimetazidine for eight weeks were observed Results: The heart function grade of patient there were greatly improved in trimetazidine treated group, LVEF was obviously increased and the LVDd was greatly reduced, respectively however the blood pressure and heart rate had no changes. Conclusion: It can be concluded that trimetazidine can greatly improve the heart function of patients with DCM, and this method is worth being popularized and utilized.更多还原