【摘要】 目的:探讨用机械通气患者发生呼吸机相关肺炎的特点及危险因素。方法:回顾性分析2001年1月-2003年6月急诊重症监护病房(ICU)用机械通气患者63例临床资料。患呼吸机相关性肺炎(VAP)31例,非VAP 32例。结果:①VAP组平均机械通气时间长于非VAP组[(17.3±15.3)d vs(6.1±3.8)d,P<0.01],VAP组机械通气时间>10d者(41.9%)多于非VAP组(9.4%),有显著差异(P=0.003)。②VAP组给予营养支持者(31.8%)少于非VAP组(71.8%),有显著差异(P= 0.004)③以是否发生VAP为因变量的Loglstic分析表明,通气时间与营养支持是发生VAP的危险因素。结论:VAP患者通气时间较长,合理营养支持的比例低,这两者可能是发生VAP的危险因素。更多还原

【Abstract】 Objective:To discuss the characteristic and risk factors of ventilator-associated pneumonia in mechanical ventilation patients. Methods: The clinical data of patients with mechanical ventilation in ICU from Jan. 2001 to Jun. 2003 were retrospectivly analyzed. Totaly 63 cases were collected,31 patients of them have VAP. The number of non-VAP patients is 32. Results:①The VAP group has a obviously longer period of mechanical ventilation than the non-VAP group[ 17. 3 ± 15. 3)d vs (6. 1 ±. 8)d P<0. 01], In the VAP group,41. 9% patients has a period of mechanical ventilation over 10 days, while 9.4% patients of non VAP group has an over 10 days ventilation period. The difference between their is significant. ②31.8% patients in the VAP group were administrated with nutrition support, which is significantly different from the non VAP group (71. 8%)(P = 0. 004).③Logistic analysis suggests that mechanical ventilation time and nutrition support are two risk factors of VAP (using occurrence of VAP as variable). Conclusion:Compared with the non-VPA group.the VAP group has relativly longer period of mechanical ventilation,and lower proportion of proper nutrition support. These may be the two risks factors of VAP.更多还原