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早发型母乳性黄疸与哺乳胎便排泄关系的调查及干预措施的研究
SURVEY ON THE RELATIONSHIP BETWEEN EARLY BREAST-FEEDING -INDUCED JAUDICE AND LACTATION AND MECONIUM EXCRETION AND SOME INTERVENTIONS
【摘要】 目的 调查新生儿早发型母乳性黄疸发病情况及病因 ,观察吗丁啉、开塞露早期干预的效果。方法 对 1~ 4日龄新生儿 2 6 3例利用经皮胆红素测定仪观察黄疸变化 ,调查胎便排泄规律、哺乳习惯 ,以及与早发型母乳性黄疸相关性 ,分别应用吗丁啉口服、开塞露灌肠对 3日龄新生儿进行干预 ,观察其干预效果。结果 2~ 4日龄新生儿早发型母乳性黄疸发生率分别为 11.0 3%、2 2 .0 5 %、2 9.2 8%和 34.99%。首次排胎便时间 ,首次排黄便时间与早发型母乳性黄疸呈明显相关(r =0 .16 ,P <0 .0 1) ;而与开始喂母乳时间的相关性不明显。应用吗丁啉、开塞露干预的第 3日龄新生儿早发型母乳性黄疸的发病例数与对照组比较 ,均有显著性差异 (P <0 .0 1)。 结论 早发型母乳性黄疸的发病与胎便排泄延迟密切相关 ,应用吗丁啉、开塞露干预是有效的手段之一。
【Abstract】 Objective To survey the occurrences of early b reast-feeding -induced jaudice and to observe the early intervention effects o f domperidone and Kaiselu.Methods 263 cases of one-to-four-day newborns underwent the percutaneous bilirubin determination to observe the chan ges of jaudice Meconium excreations,breast-feeding habits and their relationshi p with earyly breast-feeding-induced jaudiced were studied.Domperidone and kai selu were used respectively to treat the disease.Results The dete ctive rates of early breast -feeding-induced jaudices in two-to-4-day newbo rns were 11.03%,22.05%,29.58% and 34.99% respectively.The time of the first yell ow meconium excretion was closely related to the occurrence of early breast-fee ding-induced jaudices(r=0.16;P<0.01),but not to the time of initial lactati on.There existed marked differences between the 3-day newborns that received th e intervention of domperidone and kaiselu and those that did not (P<0.01). Conclusion The occurrence of breast-feeding -induced jaudice is c losely related to delayed excretion and domperidone and kaiselu have good effect s on it.
【Key words】 Newborn; Breast-feeding-induced jaudice,Early attack; Meconium excretion; Kaiselu; Domperidone;
- 【文献出处】 临沂医学专科学校学报 ,Journal of Linyi Medical College , 编辑部邮箱 ,2005年02期
- 【分类号】R722.17
- 【被引频次】3
- 【下载频次】46