【摘要】 目的:探讨颈动脉内膜 中层厚度(IMT)及斑块在判断冠心病(CHD)及其严重程度方面的价值。方法:对104例可疑或确诊的CHD患者,用高分辨率超声心动图测量双侧颈总动脉远端的 IMT、斑块与选择性冠状动脉造影结果进行对比研究,比较CHD组(62例)和非 CHD组(42 例)及 CHD各亚组间颈总动脉 IMT及斑块发生率,冠状动脉受累支数及程度与 IMT、斑块的关系。结果:①CHD患者的平均颈总动脉 IMT及斑块的发生率均显著高于非CHD组患者(P<0.01),多支病变者高于单支病变者(P<0.05)。②平均颈总动脉 IMT与CHD患者冠状动脉狭窄程度无显著相关( r=0.164,P>0.05),CHD患者中有斑块者的冠状动脉狭窄程度显著重于无斑块者(P<0.05);斑块积分与冠状动脉狭窄程度呈显著正相关( r=0.448, P<0.01)。③斑块的发生判断CHD的敏感性为40.32%,特异性为97.67%。结论:超声测量颈总动脉 IMT、斑块可间接判断 CHD的有无及其病变范围和严重程度。更多还原

【Abstract】 Objective:To study the association of coronary heart disease (CHD) with intima-media thick ness (IMT) and plaque of the common carotid artery. Method:One hundred and four patients with suspected CHD were divided into two Groups with selected coronary angiography: Group CHD (n =62) and Group NCHD(without CHD, n=42). Group CHD was subdivided into three groups according to the coronary branches involved. The IMT and plaques of common carotid arteries were measured in all patients with Echo. Result:①The incidence of plaque was higher statistically in Group CHD than that in Group NCHD.②IMT: there was significant difference between the Subgroup A and Subgroup C. The more the coronary branches were involved, the higher the incidence of the plaque was. the severity of coronary stenosis was not associated with IMT, but associated with the presence of plaque and plaque score significantly.③Plaque: the sensitivity for the diagnosis of CHD was 40.32% and the specificity was 97.6%. Conclusion:IMT and plaque of the common carotid artery are related to coronary atherosclerosis, which can be used to adjust CHD and its severity.更多还原