【摘要】 目的:探讨近10年来上消化道出血(upper gastrointestinal bleeding,UGB)的病因构成、发病趋势及与几个相关因素的关系。方法:对我院1993、1998和2003年间经内镜检查的UGB住院病人的临床资料进行统计分析。结果:(1)共检出UGB 2 347例,1993年580例、1998年646例、2003年1 121例。(2)消化性溃疡、急性胃粘膜病变、胃癌为UGB常见病因,分别占27.8%、21.1%、9.4%。(3)1993、1998和2003年三个年份中,急性胃粘膜病变分别占该年份UGB的24.3%、23.8%、17.9%;胃溃疡分别占8.3%、7.3%、4.5%;胃癌分别占6.0%、7.7%、12.0%;十二指肠溃疡分别占13.1%、19.8%、27.0%。(4)男性患者明显多于女性,男女之比为2.11∶1。(5)随着年龄的增长,UGB的发病例数增加。(6)冬春两季的发病例数明显多于夏秋两季。结论:消化性溃疡是UGB的主要原因,其次是急性胃粘膜病变、胃癌。急性胃粘膜病变、胃溃疡的发病构成比呈下降趋势,差异有统计学意义(P<0.01),胃癌、十二指肠溃疡的发病构成比呈上升趋势,差异有统计学意义(P=0.000)。UGB的病因分布与性别、年龄、季节、年代变化等因素相关。更多还原

【Abstract】 Objective:To investigate the causes,the incidence tendency and some relative factors of upper gastrointestinal bleeding(UGB) in the last ten years.Methods:Endoscopy was performed in the adults hospitalized for UGB in 1993?1998 and 2003.Results:(1)2347 UGB inpatients were enrolled in this study.There were 580 patients in 1993,646 in 1998,and 1121 in 2003.(2)The most common causes of UGB were peptic ulcer(27.8%),AGML(21.1%),and gastric cancer(9.4%).(3)The rates of AGML were 24.3% in 1993,23.8% in 1998,and 17.9% in 2003 respectively;those of gastric ulcer were 8.28%,7.28%,and 4.46%;of gastric cancer were(6.03)%,7.74%,12.04%,and of duodenal ulcer were 13.1%,(19.8)%,27.0%,respectively in 1993,1998,and 2003.(4)The male patients were more than female patients significantly.The ratio of male to female patients was 2.11:1.(5)The UGB patients increased with age.(6)The UGB patients in winter and spring were more than that in summer and autumn.Conclusion:The most common causes of UGB were peptic ulcer,AGML,and gastric cancer.In different years,the incidences of gastric ulcer and AGML had a tendency of yearly decreasing(P<0.01).The incidences of duodenal ulcer and gastric cancer had a tendency of increasing(P=0.000).Sex,age,weather alteration,and change of time were all correlative factors involved in the occurrence of UGB.更多还原