【摘要】 目的探讨青中年脑梗死与颈动脉粥样硬化的关系。方法对78例青中年脑梗死患者及30名健康对照者作颈动脉超声检查。结果(1)脑梗死组42.3%患者颈动脉内膜-中层厚度增厚(>0.8mm)与健康对照组(仅2例7.4%)比较差异有显著性(P<0.05);(2)脑梗死组动脉硬化斑块检出率为52.94%(36/68),不稳定斑块(软斑和溃疡斑)的检出率为42.03%(29/69),明显高于健康对照组(未检出);(3)多为轻度颈动脉粥样硬化(斑块积分为0.42±0.71);(4)颈动脉管腔狭窄率明显增高,以轻、中度狭窄为主(7.79%)(6/77);(5)<40岁、40~45岁、>45岁斑块发生率分别为0、33.3%和61.8%,随年龄增长,逐渐增加。结论颈动脉粥样硬化与青中年脑梗死之间存在密切关系。更多还原

【Abstract】 Objective To study the relationship between carotid atherosclerosis and with acute cerebral infarction in young and middle-aged patients. Methods 78 young and middle-aged patients with cerebral infarction and 30 normal control subjects were examined with color Doppler sonography. Results The cases with thickening endarterium-intercellular layer (>0.8 mm) of carotid artery in patient group (42.3%) were more than those in control group (7.4%)((P<)0.05). In patient group, 52.94% of the patients (36/68) were detected with atherosclerotic plaque, and 42.03% of the cases (29/69) were astable plaques (soft plaque and ulcer plaque). No case with atherosclerotic plaque was found in control group. Slight and moderate stenoses of carotid arteries were detected in 7.8% of the patients (6/77), while severe stenoses accounted for 2.6%. The detecting rates of atherosclerotic plaque increased as aging of the patients. They were 0% (<40 yrs), 33.3% (40～45 yrs) and 61.8% (>45 yrs).Conclusion Cerebral infarction in young and middle-aged patients is closely related to atherosclerosis of carotid artery.更多还原