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联用自体红骨髓与骨肽注射液治疗骨不连
Treatment of nonunion with combination of autogenous red blood marrow and osteopeptide injection
【摘要】 目的 探讨联用自体红骨髓与骨肽注射液注入骨折处治疗骨不连的疗效。方法 X线机或C臂X线机确定骨折间隙,取自体红骨髓与骨肽注射液经皮注入到骨折端间隙、骨膜及骨膜周围, 间隔 2周注射 1次,连续治疗 4次。结果 52例中, 50例从治疗起 1~1 5个月形成骨痂, 3~6个月骨愈合; 2例因骨折端假关节形成改为手术治疗。结论 自体红骨髓与骨肽注射液联用注入骨不连部位具有明显的成骨作用,骨肽注射液可诱导红骨髓细胞转化为成骨细胞。
【Abstract】 Objective To investigate the effect of autogenous red blood marrow and osteopeptide injection for nonunion. Methods With radiograph or image intensifier,the nonunion sites were localized,and autogenous red blood marrow and osteopeptide were injected into the interfragment spaces,periosteum and around periosteum. Results 52 cases received this treatment, of which 50 got bony union.The callus was found in 1~1.5 months. The bony union time was 3~6 months. 2 cases with pseudoarthrosis formation received operation. Conclusions It provides obvious osteogenesis effect in the treatment of nonunion with combination of autogenous red blood marrow and osteopeptide injection.Osteopeptide can induce red blood marrow cells to defferentiate to osteoblasts.
【Key words】 fractures,nonunited; red bone marrow autograft; osteopeptide; combined modality therapy;
- 【文献出处】 临床骨科杂志 ,Journal of Clinical Orthopedics , 编辑部邮箱 ,2005年01期
- 【分类号】R683
- 【被引频次】9
- 【下载频次】85