【摘要】 观察川芎嗪联合苦参秦治疗慢性乙肝的疗效。86例患者随机分为两组,对照组(B组)36例给苦参素及常规护肝药;治疗组(A组)50例在对照组基础上联用川芎嗪(40-80)mg/日,静脉滴注,疗程均为4周。结果:治疗4周后,治疗组ALT及TBil复常率分别为92%、96%,对照组分别为55.5%,77.7%,两组间有显著性差异(P< 0.05),HBV DNA及HBeAg阴转率略高于对照组,但无统计学差异。川芎嗪联合苦参素明显改善肝功能且抑制DNA 复制,是治疗慢性乙肝的有效联合。更多还原

【Abstract】 to observe the efficacy of chronic hepatitis B with ligustrazine and oxymatrine, 86 cases were randomly divided into the test group and the control groap.the control group (36 cases) was treated with oxymatrine and common liver protecting medicines, the test group (50 cases) was treated also with the same drags but adding ligustrazine (60 - 80mg)/d by intravenous drip for 4 weeks. 4 weeks later, ALT recovery rate and TBil recovery rate of the test group were 92 % and 96 % , while control group were 55. 7% and 77.7% respectively, the difference was significantly ( P < 0.05) . the HBV DNA and the HBeAg serocoversion rate in test group was slightly higher than that of control group. The paper indicated the treatment of chronic hepatictis B with ligustrazine and oxymatrine is more effective than with only oxymatrine.更多还原