【摘要】 目的探讨检测血清前白蛋白(PA)在肺结核病中的临床应用价值。方法采用免疫透射比浊法分别检测310例健康体检者和287例肺结核病人治疗前后血清PA及谷丙转氨酶(ALT)、谷草转氨酶(AST)。结果在肺结核病人治疗前与健康体检者的血清PA检测结果相比较无显著性差异(P>0.05);经抗结核治疗后血清PA的检测结果降低(P<0.05),尤其随着疗程的延长血清PA水平降低更为显著(P<0.01);在抗结核治疗早期血清PA的阳性率为87%,高于ALT和AST的阳性率(34%)。结论血清PA检测可作为抗结核治疗后的常规肝功能指标,尤其适用于抗结核治疗后肝功能早期损害程度的判断。更多还原

【Abstract】 Objective To study the clinical application of detecting prealbumin (PA) in serum for pulmonary tuberculosis.Methods PA in 310 normal healthy controls and 287 patients with pulmonary tuberculosis before and after therapy were detected by immunoturbidimetry. At the same time , ALT and AST were detected in the controls. Results There were no significant difference in PA between normal controls and patients with pulmonary tuberculosis before therapy (P>0.05); there was significant difference between before the therapy and after the therapy(P<0.05), the positive rate of PA in patients with anti-tuberculosis treatment early was 87%, which was higher than those of ALT and AST (34%).Conclusion The detecting PA might be used as an routine liver function index of patients with pulmonary tuberculosis. It also gives objective evidence to the determination of liver function early damage after anti-tuberculosis treatment.更多还原