【摘要】 目的　探讨蛇毒血凝酶治疗肺结核大咯血的临床价值。方法　将1 2 7例肺结核大咯血患者随机分为2组,治疗组给予蛇毒血凝酶IKU肌肉注射;对照组给予垂体后叶素5U静脉注射,继用1 0U加入5 %葡萄糖液50 0ml中静脉滴注并加以观察。结果　两组在咯血停止时间上差别不明显;而在2 4h内复发率、不良反应发生率方面,蛇毒血凝酶明显优于垂体后叶素。结论　蛇毒血凝酶具有使用安全、方便、可靠,防复发效果好,无明显不良反应,禁忌症少,应用范围广泛的优点,具有临床推广价值。更多还原

【Abstract】 Objective. To study the effects of hemocoagulase on massive hemoptysis caused by PTB. Methods 127 cases with massive hemoptysis due to PTB were randomly divided into study group and control group. Each of the cases in the study group was given an intravenous injection of 1 KU of hemocoagulase. 5 U of pitressin was venously injected to each of the cases in the control group, followed by venous transfusion of 10 U of pitressin and 500ml of 5% glucose. Results There was no difference in hemoptysis stopping between the two groups, but the recurrence rate 24 hours after the injection and the incidence rate of adverse reaction in the study group were significantly lower than those in the control group. Conclusion. Hemocoagulase may have some advantages such as being safe, convenient and reliable, and with lower recurrence rate, less adverse reaction, and less contraindication. It is suggested for wider use.更多还原