【摘要】 目的:研究氟化物控释装置(IFRD)对细菌在牙科常用合金表面粘附的影响。方法:将抛光后的Co-Cr合金和Ti合金试样各均分为8组,测定表面粗糙度后在无IFRD环境中(A、B、C、D组)和IFRD环境中(A1、B1、C1、D1组)进行细菌粘附实验,并分别于1 h、4 h、8 h、24 h取出,测定各组样本表面细菌粘附面积百分比并进行统计学检验。结果:Co-Cr合金A、B、C、D、A1、B1、C1、D1各组样本表面粗糙度分别为(0.171±0.012)μm、(0.169±0.013)μm、(0.171±0.015)μm、(0.172±0.012)μm、(0.170±0.011)μm、(0.168±0.009)μm、(0.174±0.015)μm、(0.172±0.010)μm,其细菌粘附面积比分别为(19.56±5.75)%、(30.12±6.48)%、(48.94±5.37)%、(79.28±8.19)%,(10.82±3.13)%、(13.04±4.36)%、(17.96±4.86)%、(24.38±5.89)%;钛合金A、B、C、D、A1、B1、C1、D1组表面粗糙度分别为(0.292±0.003)μm、(0.295±0.014)μm、(0.289±0.011)μm、(0.290±0.010)μm、(0.291±0.009)μm、(0.290±0.013)μm、(0.294±0.016)μm、(0.291±0.011)μm,其细菌粘附面积比分别为(24.36±5.59)%、(35.28±6.87)%、(51.45±5.82)%、(82.03±7.69)%.(16.15±4.31)%、(18.34±4.95)%、(22.59±6.90)%、(31.17±4.27)%。经统计学分析表明,无论是Ti合金还是Co-Cr合金使用IFRD后细菌粘附面积比均显著少于未使用IFRD组(P<0.01)。结论:IFRD对细菌在金属表面的粘附有明显的抑制作用,可减少菌斑的附着。更多还原

【Abstract】 Objective: This study investigated the effect of IFRD on adhesion of oral micro-organisms on Ti alloy and Co-Cr alloy in vitro. Methods: 48 pieces Ti alloy were divided into 8 groups and their surface roughness were measured by 6AJ interference microscope. A, B, C, D groups were used for micro-organisms adhesive test without IFRD and A₁, B₁, C₁, D₁ groups were used for same purpose with IFRD. A standardized cell suspensions were incubated with all test samples for 1h, 4h, 8h 24h at 37oC and retained cells were counted by image analysis. The 48 pieces Co-Cr alloy were treated with same procedure of Ti alloy. Results:Roughness values and percentage area of a microscopic field covered by cells of A, B, C, D, A₁, B₁, C₁, D₁ groups of Co-Cr alloy were （0.171±0.012） μm、（0.169±0.013） μm、（0.171±（0.015）） μm、（0.172±0.012） μm、（0.170±0.011） μm、（0.168±0.009） μm、（0.174±0.015） μm、（0.172±（0.010）） μm, （19.56±5.75）%、（30.12±6.48）%、（48.94±5.37）%、（79.28±8.19）% , （10.82±（3.13））%、（（13.04）±（4.36））%、（17.96±4.86）%、（24.38±5.89）%. The values of A, B, C, D, A₁, B₁, C₁, D₁ groups of Ti alloy were （0.292±0.003） μm、（0.295±0.014） μm、（0.289±0.011） μm、（0.290±0.010） μm, （0.291±0.009） μm、（（0.290）±0.013） μm、（0.294±0.016） μm、（0.291±0.011）μm, （24.36±5.59）%、（35.28±6.87）%、（51.45±（5.82））%、（82.03±7.69）%、 （16.15±4.31）%、（18.34±4.95）%、（22.59±6.90）%、（31.17±4.27）%. There were significantly difference of percentage area of a microscopic field covered by cells between groups with and without IFRD of Ti alloy and Co-Cr alloy. Conclusions: There was a significantly influence of IFRD on adhesion of oral micro-organisms on Ti alloy and Co-Cr alloy.更多还原