【摘要】 目的 :重症肌无力 (MG)是自身免疫性疾病 ,常伴有胸腺增生及胸腺瘤 ,需针对免疫学特点而治疗 .方法 :采用激素合并吡啶斯的明治疗 ,并行胸腺CT或MRI检查 ,对有胸腺增生或胸腺瘤者采用手术切除 .结果 :75例好转 ,2例死亡 ,10例复发者均为激素治疗时间过短 ,6例并发糖尿病 .结论 :MG患者常规行胸腺CT或MRI检查 ,发现有胸腺瘤及胸腺增生者应早期行手术治疗 ,同时用激素与吡啶斯的明治疗 ,治疗期间定期验血糖 ,一旦发现糖尿病及早治疗 ,并停用激素 ,换用免疫抑制剂治疗 .更多还原

【Abstract】 Objective: Myasthenia gravis(MG) is an autoimmune disease,the patients with MG are commonly diagnosed with thymoma or thymic hyperplasia and other autoimmune disorders, The plan for management will be based on the immunological characteristics.Methods: Anticholinesterase drugs and corticosteroid are the most treatment modalities, all patients’ thymuses were scanned with CT or MRI, thymectomy was indicated for MG with thymoma.Results: In 77 cases of MG treated, 75 cases improved, 2 cases died.10 cases of recurrence were used to being treated by corticosteroids too shortly, 6 cases complicated diabetes.Conclusion: Most patients with MG often took thymic CT or MRI scan, the patients with thymoma or thymic hyperplasia can receive thymectomy in the early concurrent administration with anticholinesterase agents and corticosteroids.In the period of treatment must test glucose, when finding glucose heightening, the treatment for diabetes must be considered and corticosteroids should be given up and substituted by other immunosuppression.更多还原