【摘要】 树突状细胞(Dendritic cells,DCs)是最有效的抗原呈递细胞。DCs能够摄取外来物质,包括结核分枝杆菌(Mycobac teriumtu berculosis,MTB),并将其呈递给效应性淋巴细胞,激发宿主对抗病原微生物感染的免疫反应。因此,树突状细胞与结核分枝杆菌的相互作用在感染初期机体发动免疫应答中十分重要。研究树突状细胞和结核分枝杆菌间的相互作用,有利于从根本上了解细菌-宿主作用机理,为阐明结核分枝杆菌逃避免疫的机制提供依据。更多还原

【Abstract】 Dendrtic cells(DCs) are most efficient antigen presenting cells. DCs can uptake pathogens, including Mycobacterium tuberculosis(MTB), and then present to T cells to active anti-pathogen immune responses. So the interaction between DCs and MTB is of great importance in initiating an immune response in early the stage of infection. The researches on this interaction can help to comprehend infection mechanism and provide evidence about MTB escaping from immune responses.更多还原