【摘要】 目的:考察注射用奥沙利铂与葡萄糖注射液、木糖醇注射液以及果糖注射液配伍后的稳定性。方法:考察注射用奥沙利铂与葡萄糖注射液(GS)、木糖醇注射液及果糖注射液配伍后溶液的外观性状、pH值及含量等。结果:注射用奥沙利铂与葡葡糖注射液及果糖注射液配伍8 h,其含量均在95%以上,外观性状及pH值均无明显变化;注射用奥沙利铂与木糖醇注射液配伍8 h,pH值、含量逐渐降低。结论:注射用奥沙利铂在临床应用时宜采用葡萄糖注射液及果糖注射液进行配伍使用,不宜与木糖醇注射液配伍使用。更多还原

【Abstract】 Objective:To investigate the stability of compatibility between oxaliplatin injection and glucose Infusion,or xylitol infusion,or fructose infusion. Methods:To observe solutions appearance , pH values, oxaliplatin level and etc., following compatibilities testing of oxaliplatin injection with glucose infusion,xylitol infusion,and fructose infusion. Results: After 8 hours compatibility testing between both oxaliplatin for injection and glucose infusion as well as oxaliplatin injection and fructose infusion, the contents of each maintain more than 95%. Their appearance, properties and pH values have no significant change. After 8 hours compatibility between oxaliplatin injection and xylitol infusion, the solutions pH values and content were gradually decreased.Conclusion:ln clinical application, oxaliplatin injection should adopt glucose infusion and fructose infusion rather than xylitol infusion for compatibility.更多还原