节点文献

Ⅱ、Ⅲ期结直肠癌临床病理特征分析

Clinical and pathological character analysis of colorectal cancer instage Ⅱ and Ⅲ

  • 推荐 CAJ下载
  • PDF下载
  • 不支持迅雷等下载工具,请取消加速工具后下载。

【作者】 万相斌潘志忠丁培荣万德森

【Author】 WAN Xiang-bin,PAN Zhi-zhong,DING Pei-rong,WAN De-sen (Department of Abdominal Surgery, Tumor Hospital,Sun Yat-Sen University, Guangdong Guangzhou 510060, China)

【机构】 中山大学肿瘤医院腹科中山大学肿瘤医院腹科 广东广州510060广东广州510060广东广州510060

【摘要】 目的结直肠癌中,Ⅱ、Ⅲ期患者占绝大多数,本研究通过分析Ⅱ、Ⅲ期结直肠癌的临床病理特征,探讨其特点。方法分析1990~1999年我院收治的Ⅱ、Ⅲ期结直肠癌患者的临床及病理资料,比较Ⅱ、Ⅲ期患者中各初发症状,性别,年龄、病程,肿瘤部位,合并症,大体类型,组织类型及病理分级的差异。结果粘液血便是结直肠癌患者最常见的初发症状;肿瘤部位多见于直肠,以腺癌为主。Ⅱ、Ⅲ期相比,腹痛及大便习惯改变的发生率的差异有统计学意义;升结肠癌、直肠癌,大于5cm的肿瘤、严重贫血,乳头状腺癌,Ⅱ级及Ⅲ级肿瘤的出现率的差异也有统计学意义。结论Ⅱ、Ⅲ期结直肠癌虽然存在着某些差异,但为疾病的延续和进展,只有对早期症状重视,才能早期发现。

【Abstract】 Objective: To investigate and analyze their clinical and pathological characters of the colorectal cancer patients, majority of which are in stage Ⅱ and Ⅲ. Methods: The date of colorectal cancer was statistically analyzed in stage Ⅱ and Ⅲ from 1990 to 1999 in the Cancer Hospital of Sum Yat-sen university, including in primary site, gender, age, symptom, tumor location, complication, tumor size, gross findings, histology and pathological grades. Results: The classical and frequent initiating symptom was muciferous bloody stools, which suggested rectocarcinoma and adenocarcinoma mostly. Compared stage Ⅱ with stage Ⅲ, the frequency of abdominal pain, change in bowel habit, ascending and rectal tumor, more than 5cm tumor, serious anemia, grade Ⅱ and Ⅲ tumor was statistical significance. Conclusion: There exists some difference between colorectal cancer in stage Ⅱ and Ⅲ, which is caused by the advance of disease. The tumor can not be early diagnosed unless the symptoms are early paid attention to.

【关键词】 结直肠癌Ⅱ、Ⅲ期临床病理特征
【Key words】 colorectal cancerstage Ⅱ and Ⅲ