【摘要】 目的观察肝硬化顽固性腹水病人应用自体腹水分次回输联合多巴胺及呋塞米的治疗效果。方法70例肝硬化顽固性腹水患者分为两组。对照组34例应用自体腹水分次回输治疗;观察组36例采取自体腹水分次回输联合多巴胺及呋塞米治疗。结果两种方法均取得较好疗效,治疗后血清白蛋白增加,肾功能改善,电解质无明显变化,腹水逐渐消退,但观察组治疗次数及回输腹水量比单纯行自体腹水回输均减少(P<0.05),尿量增加更为显著(P<0.05)。结论腹水回输联用多巴胺及呋塞米能舒张肾脏血管,增加肾血流量和肾小球滤过率,增强利尿。更多还原

【Abstract】 Objective To observe the therapeutic effect of self-ascites back transfusion plus dopamine and furosemide on stubborn ascites resulting from hepatocirrhosis. Methods All the 70 patients with stubborn ascites resulting from hepatocirrhosis were divided into observing group (36) and control group (34). The control group was treated with self-ascites back transfusion for several times, and the observing group was treated with combined dopamine and furosemide additionally.Results Although both of the two groups reached good therapeutic effects on some aspects, the back transfusion times and amount were significantly fewer and less in observing group than in control group (P<0.05), and the urine volume of the observing group increased more obviously (P<0.05). Conclusion Back transfusion of ascites combined with dopamine and furosemide can enforce the urination of the patients with stubborn ascites resulting from hepatocirrhosis because of the dilation of nephric blood vessels and the increase of nephric blood flow and glomerular filtration rate.更多还原