【摘要】 目的探讨放射性核素全身骨显像中单发病灶的临床价值。方法受检者常规99Tcm—亚甲基二膦酸盐(MDP)骨显像,对310例骨显像中单发病灶进行临床分析。结果有肿瘤病史的256例患者,骨转移率为24.2%(62/256),无肿瘤病史的54例患者中,骨转移率为5.5%(3/54),两者差异有显著性;总骨转移率为20.9%(65/310)。其中前列腺癌20.8%(5/24),乳腺癌22.4%(17/76),肺癌32.7%(18/55),泌尿系肿瘤23.1(3/13),消化系肿瘤16.7%(7/42),其他肿瘤26.1%(12/46),无肿瘤病史患者中,94.4%(51/54)的单发病灶主要是良性病灶。结论在骨显像单发病灶中,有原发肿瘤病史患者24.2%为早期骨转移灶,无原发肿瘤病史患者94.%主要为良性改变。初步得出了全身骨显像中单个病灶临床分析标准和价值。更多还原

【Abstract】 Objective To study clinical value of whole bone scanning of solitary lesions. methods The whole bone scanning followed routine procedures.The imaging agent was 99Tcm--MDP. To analyze solitary lesions in 310 patients on whole bone scanning. Results The rate of bone metastasis was 24.2% in 256 patients with primary malignancy. The rate of bone metastasis was 5.5% in 54 patients without primary malignancy, and the total diagnostic rate of bone metastasis was 20.9% in 310 patients. There were significant differences between two groups. In patients with primary malignancy, the incidences of bone metastasis of solitary lesions were as follows: prostate cancer 20.8%(5/24) , breast cancer22.4%(17/76), bronchicancer32.7% (18/55), other urinary cancer 23.1%(3/13), gastrointestinal cancer 16.7%(7/42),other cancer 26.1%(12/46),in patients without primary malignancy 94.4% (51/54) of solitary lesions were benign. Conclusion The diagnostic rate of bone metastasis in solitary lesions was 24.2% with primary malignancy .In patients without primary malignancy, 94.4% were benign. We have obtained a clinical analysis procedures and value for diagnosis of solitary lesions.更多还原