【摘要】 目的了解我院17年来临床假丝酵母菌的感染情况和种类分布及对12种药物的抑菌效果,为临床提供帮助。方法真菌的分离和鉴定,按全国临床检验操作规程假丝酵母菌的有关要求进行。药敏实验采用扩散法。结果72220份标本共分离8种假丝酵母菌4652株,检出率6.4%,其中以白色假丝酵母菌为主,其次是类星形、热带、高里、皱褶假丝酵母菌等,分别占总数的33.7%、20.4%、14.5%、11.1%、10%。7类标本中痰液检出最多,达35%。8种假丝酵母菌对GRIS均耐药,TEB仅部分敏感,大多数热带假丝酵母菌对ECON呈中度敏感。结论临床上假丝酵母菌感染比较严重,且常与细菌合并感染。扩散法药敏实验操作简单、结果稳定,适用于常规实验。更多还原

【Abstract】 Objective To understand the specific distnbudon of yeast fmgalint)ction and antifungal effects of 12 kinds of drugs in our hoqoital in recently 17 years, and to provide help for clinical treatment. Methods Fungi were isolated and identified according to the national clinical experinental operadonal rules about yeast fungi, and drug suscepbbilties were detected bydisk diffuse way. Results 4652 strains of yeast fungi with 8 types were isolated fran 72220sampies (6.4%).C.albicans, C.stellatoidea, C.tropicals, C.guilliermondi, C.xugosa were accounted for 33.7%,20.4%,14.5%,11.1% and 10% respectively.The detectibe rate of sputum sample was the highest(35%)among 7 kinds of qoecinens. The results showed all 8 types yeast fungi were resistant to GRIS, partly susceptible to TEB.The major of C.tropicals were moderately sumscepbble to ECON .Conclusions The yeast fungal infection is severe and usually happen fillowing germ infection in clinic. The disk diffuse way is fit to routine experinet because of its easy cperedon and stable result.更多还原