【摘要】 采用晶体生长抑制剂技术,制备了超细水杨酸晶体。以相对分子质量为600的聚乙二醇为水杨酸晶体生长抑制剂时,制备的水杨酸针状体的直径范围为100nm~5μm。当聚乙二醇的相对分子质量为2000时,制备的水杨酸针状体的直径范围为500nm~5μm。在水杨酸晶体生长过程中,通过聚乙二醇的羟基与水杨酸的羧基的相互作用控制了水杨酸晶体的大小。用季戊四醇为水杨酸晶体生长抑制剂时,制备出了平均直径为8μm的棒状水杨酸晶体。更多还原

【Abstract】 Extra-fine salicylic acid crystallites were prepared by using crystal growth inhibitors such as polyethylene glycol and pentaerythritol.When polyethylene glycol with average molecular weight of 600 was used as crystal growth inhibitor,needle-like salicylic acid crystallites with diameters ranging from 100 nm to 5 μm were prepared.Needle-like salicylic acid crystallites with diameters ranging from 500 nm to 5 μm were prepared using polyethylene glycol with average molecular weight of 2000 as crystal growth inhibitor.The interaction between hydroxyl group of polyethylene glycol and carboxyl group of salicylic acid inhibited the crystal growth of salicylic acid.When pentaerythritol was used as the inhibitor,bar-like salicylic acid crystallites were prepared with average diameter of 8 μm.更多还原