【摘要】 在碱催化条件下,以对叔丁基酚为底物,与甲醛和吗啉进行Mannich反应,制备了4 叔丁基2, 6 二(4 吗啉甲基)苯酚。最佳工艺条件为: 80℃回流反应8h,w(NaOH) =10%的水溶液进行催化,收率83 8%。并通过红外光谱、核磁共振氢谱和碳谱对目标产物进行了结构表征。更多还原

【Abstract】 Starting with 4-t-butylphenol,morpholine and formaldehyde,4-t-butyl-2,6-bis（4-morpholinomethyl）-phenol (C₂₀H₃₂N₂O₃) was synthesized through Mannich reaction catalysed by base.The optimum technological conditions were investigated.Thus,refluxing at 80 ℃ for 8 h with 10% NaOH aqueous solution as catalyst,the yield reached 83.8%.Structure of the product was determined by IR,¹³CNMR and ¹HNMR.更多还原