【摘要】 目的探讨特发性股骨头缺血性坏死发病的主要危险因素以及因素间的交互作用和联合作用。评估各危险因素的相对重要性。方法运用1∶1病例对照研究设计,用多因素条件Logistic逐步回归分析。结果轻微创伤、每周饮酒量、饮茶习惯和激素使用为特发性股骨头坏死发病的危险因素。饮茶因素是特发性股骨头坏死发病的保护因素,激素使用、长期大量饮酒以及轻微创伤之间与特发性股骨头坏死发生存在着联合作用。促进因素越多,特发性股骨头坏死发病的危险越高。结论对特发性股骨头坏死危险因素进行全面分析,为临床早期发现、早期诊断和早期治疗该病提供理论依据,对该病高危人群针对性预防具有重要意义。更多还原

【Abstract】 Objective To explore the main risk factors of idiopathic avascular necrosis of femoral head(IANFH) and the interactions and joint actions among these risk factors and to evaluate the relative importance among these risk factors. Methods 1∶1 paired case-control study design and multivariate conditional logistic stepwise regression was applied to our epidemiological study. Results This study suggested that slight trauma, volume of drinking alcohol per week, using cortical steroid and drinking tea serve as independent risk factors of IANFH. Drinking tea is only protecting factor of IANFH. The joint actions are found among the three risk factors ∶using cortical steroid, volume of drinking alcohol per week, slight trauma. The more promoting factors, the higher incidence of IANFH.Conclusion To carry out overall analysis for the risk factors of IANFH provides a theoretical basis for early discovery and early diagnosis and early treatment of IANFH and has important meaning for the prevention of specific aim of the high dangerous crowd.更多还原