【摘要】 较详细的综述了钌-手性膦配体催化剂在不对称催化氢化反应中的最新应用进展,主要从钌-手性膦配体催化剂在芳基丙烯酸(萘普生、布洛芬等)、酰胺类化合物、酮酯等方面的不对称催化反应中的应用进行综述,文章从催化剂活性、立体选择性、转化率和对映选择性等角度讨论了各种合成方法的优点及不足。更多还原

【Abstract】 The application and recent research progress on the asymmetric hydrogenation of the arylpropaoicacid (Naproxen, Ibuprofen and so on), acylamine, ketone and ester by ruthenium-chiral phosphine-catalysts are reviewed in this article in detail. The advantage and disadvantage of various synthesis methods are discussed from the aspects of catalytic activity, steroselectivity, conversion and enantiselectivity on the basis of 33 references.更多还原