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经皮穿刺植入125I粒子治疗恶性肿瘤的临床应用
Clinical application of percutaneous implantation of 125I seeds for treating malignant tumor
【摘要】 目的根据内放射源125I粒子的物理特性探讨其治疗原理、治疗计划系统(TPS)的意义、治疗方式及临床疗效。方法18例晚期肿瘤患者采取经皮穿刺植入125I粒子行组织间放疗。结果18例肿瘤患者均未出现任何严重的并发症,生存质量明显提高。2个月后经胸片、CT复查18例患者肿瘤均有不同程度缩小,12例明显缩小,其中5例肿瘤基本消失。结论短期疗效证明,125I粒子组织间放疗对晚期肿瘤效果显著,不良反应小。
【Abstract】 Objective To investigate the therapeutic mechanism of 125I seeds based on physical properties, the significance of therapeutic planning system (TPS), the therapeutic means and the clinical efficacy. Methods Eighteen cases with advanced carcinoma were treated through percutaneous implantation of 125 I for interstitial radiotherapy. Results No serious complications occurred in the patients after radiotherapy associated with apparent improved living quality. Two months after therapy, the tumors had shrunk in different degrees with conspicuous decrease in 12, of which 5 tumors disappeared. Conclusions Short-term efficacy demonstrates that intra-tissue radiotherapy of 125I had significant efficacy for advanced tumors.
【Key words】 125I; Therapeutic planning system; Advanced tumors; Therapeutic methods;
- 【文献出处】 介入放射学杂志 ,Journal of Interventional Radiology , 编辑部邮箱 ,2005年04期
- 【分类号】R730.5
- 【被引频次】22
- 【下载频次】62