【摘要】 目的评价介入治疗在儿童肾母细胞瘤、肾血管性病变及输尿管狭窄的应用。方法共治疗38例患儿。对18例肾母细胞瘤患儿行术前肾动脉造影及灌注化疗加栓塞术。13例不明原因的高血压行肾血管造影及血浆肾素水平的测定,并对部分患儿行PTA治疗。6例输尿管狭窄行球囊扩张。1例血尿患儿行小动脉栓塞术。结果栓塞术后肾母细胞瘤肿瘤血管减少,受肿瘤影响的病肾缩小,肿瘤周围组织与正常组织分界清晰,减少肿瘤细胞进入血流及向远处转移。肾血管性高血压得到了明确诊断及治疗。输尿管梗阻得到改善。结论介入治疗在泌尿系统应用是完全可行的,有着广泛的临床应用价值。更多还原

【Abstract】 Objective To evaluate the role of interventional therapy in Wilm’s tumor, renal vascular lesions and ureter stricture in children. Methods Thirty-eight cases were analysed, including 18 cases of Wilm’s tumor treated with preprocedural chemotherapy and embolization through renal artery, and 13 cases of unknown-reason hypertension with selective renal arterial angiography for venous blood renin including undergone some patients PTA. Six cases of ureter stricture were dilated with balloon and 1 with hematurea by small aerial embolization. Results After embolization, Wilm’s tumors showed reduction in vascularization and reduction in size too. The surrounding tissue of the tumor had a clear demarcation with the normal tissue, decreasing the dissemination to blood and distal metastasis. Renal vascular hypertension was clearly diagnosed and treated, and the increase of renin was helpful to the diagnosis of unknown-reason hypertension. And the obstruction of ureter was improved. Conclusions Interventional therapy is feasible in the application of urinary system diseases with great significance clinically.更多还原