【摘要】 目的:探讨脉冲组织多普勒成像(PW-DTI)技术速度指标在定量评价冠状动脉疾病(CAD)左心室局部收缩、舒张功能方面的应用价值。方法:CAD组47例,正常对照组30例。根据冠状动脉造影(CAG)结果,将231 支冠脉分为正常组、轻度狭窄组、中度狭窄组和重度狭窄组。采用PW-DTI技术检测左心室前间隔、后壁、前壁、下壁、侧壁以及后间隔各基底段和中间段共计12个节段的瞬时心肌运动速度,即收缩期峰值速度(Sm)、舒张早期峰值速度(Em)和舒张晚期峰值速度(Am),并计算Em/Am比值。结果:轻度狭窄组冠脉对应节段的Am高于正常组(P<0.05),两组之间的Sm、Em的差异无显著性意义(P>0.05)。中度狭窄组部分对应节段的Sm、Em、Am与正常组的差异有显著性意义(P<0.05)。重度狭窄组所有对应节段的Sm、Em、Am与正常组的差异有显著性意义(P< 0.05)。结论:PW-DTI技术通过定量检测室壁运动速度,能够客观地反应左心室局部收缩、舒张功能。更多还原

【Abstract】 Objective: To assess the regional systolic and diastolic function of left ventricle by pulsed wave Doppler tissue imaging ( PW-DTI) in patients with coronary artery disease ( CAD ) . Methods : Seventy-seven cases of coronary angiography were adopted for study and grouped in terms of severity of coronary arterial lesion. Peak systolic, peak early diastolic, and peak late diastolic motion velocities (Sm, Em and Am, respectively) were recorded at 6 different sites on the basal and medial segments corresponding to the anteroseptal, posteroseptal, lateral, anterior, inferior, and posterior walls of the left ventricle with PW-DTI. Results: Am in segments corresponding to normal coronary arteries (group A) was lower than in segments corresponding to slightly stenosed coronaries (group B). There was no significant difference in Sm and Em between group A and group B. Compared with group A, Sm, Em and Am were significantly decreased in segments corresponding to severely stenosed coronary arteries ( group D). Conclusion : PW-DTI could be used to evaluate quantitatively and accurately the regional mvocardial function of left ventricle in patients with CAD.更多还原