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Determination of Aconitine in Medicinal Wine and Its Dosage of Aconitine Poisoning

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ã€Authorã€‘ ZHANG Hong-gui~1,MA Chen~2,WU Yi~3,LIU Ai-ru~2,ZHANG Han-qi~1(1.College of Chemistry,Jilin University,Changchun 130012,China;2.Institute of Materia Medica,Chinese Academy of Medical Sciences,Beijing 100050, China;3.Second Hospital,Jilin University,Changchun 130041,China)

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ã€Abstractã€‘ A modified HPLC method was used for the separation and the determination of aconitum alkaloids in(medicine) wine.The toxical dosages of the preparations were established on the basis of the data from the above determination.At the same time,the chemical reasons of aconitine poisoning were revealed.These(reasons) have provided some scientific bases for the clinical safe drug use.æ›´å¤š è¿˜åŽŸ