【摘要】 目的探讨心脏机械瓣膜置换术后抗凝药物的应用及相应监测指标。方法回顾性分析1999年5月～2004年5月,本院30例心脏机械瓣膜置换术后,华法林的应用情况及随访结果。结果本组无术后死亡病例,除1例术后服药期间出现迟发性心包积血,2例出现皮肤瘀斑、青紫,调整用量后好转,其余患者效果良好。结论心脏机械瓣膜置换术后需要终生服用华法林抗凝治疗,正确掌握抗凝治疗是减少患者换瓣术后并发症,提高生活质量的重要环节。更多还原

【Abstract】 Objective To investigate the application of anticoagulation therapy after heart mechanical valve replacements and corresponding inspection. Methods From May 1999 to May 2004,clinical data of 30 cases of the application of anticoagulation therapy after heart mechanical valve replacements were retrospectively analyzed.Results There were no death due to operation except that 1 patient was found chronic pericardial effusion;2 patients were found cyanosis and gore because of haemorrhage during application of anticoagulation therapy after operation. All patients were very well.Conclusion The patients need the application of anticoagulation therapy after heart mechanical valve replacements in lifetime. The correct application of anticoagulation therapy can reduce complication and enhance life quality after heart mechanical valve replacements.更多还原