【Abstract】 A highly selective and rapid new anodic adsorptive voltammetric method was developed for the determination of ultra trace amount of pipemidic acid at a carbon paste electrode（CPE）.The pipemidic acid is adsorbed on the surface of the CPE in 0.64mol·L^-1NH₄Ac-HAc buffer solution（pH4.90）and yields one oxidation peak at 1.05V（vs.SCE）when nearly scanning from 0.8 to 1.8V.The relationship between the peak current and pipemidic acid concentration is linear in the range of 2.0×10^-9to 2.0×10^-7mol·L^-1with the correlation coefficient 0.995.Its detection limit is 6.0×10^-10mol·L^-1（S/N=3）for 150s accumulation.The proposed method was applied to determine the trace of pipemidic acid in the urine samples.更多还原