【摘要】 [目的]描述1996—2004年间福建省围生儿唇裂畸形的流行病学特征。[方法]调查22所县级以上监测医院分娩的孕28周至产后7 d的围生儿。[结果]围生儿总唇裂发生率为12.61/万。其中唇裂4.86/万,唇裂合并腭裂7.75/万;城镇发生率11.44/万,乡村14.21/万;男性14.26/万,女性10.40/万。产妇年龄组间总唇裂发生率类似,年度发生率下降不显著。总唇裂畸形中以单发多见(80.6%),围生期病死率29.7%,其中单发畸形20.0%,多发70.1%。[结论]我省总唇裂发生率下降趋势不显著,仍是我省发生率第一位的先天畸形,男性发生占优势。更多还原

【Abstract】 To describe the epidemiological features of perinatal cleft lip with or without cleft palate(CL±P) from 1996 to 2004 in Fujian.All live or still births with 28 weeks of gestation to 7 days after birth were assessed in 22 surveillance hospitals.\The prevalence rate of CL±P was 12.61/10 000(CL and CLP were 4.86/10 000 and 7.75/10 000 respectively).The rates were 11.44/10 000 and 14.21/10 000 in urban and rural area,and 14.26/10 000 and 10.40/10 000 in male and female respectively.There was no significant difference among maternal-age-specific prevalence rates.And no decreasing trend was found during this period.The rate of isolated form in CL±P was 80.6%.The perinatal fatality rate of CL±P was 29.7%,and the rate in isolated forms was 20.0%,and in syndromic was 70.1%.No decreasing trend of prevalence rate of CL±P was observed during 1996-2004.It is still the highest (preva)lence of birth defect in Fujian and males were predominant in this defect.更多还原