【摘要】 目的分析异常核型与不良生育之间的关系。方法对593对不良孕产史夫妇进行细胞遗传学检查。结果发现染色体异常核型38例,异常发生率为3.2%。其中平衡易位31例(相互易位16例,罗伯逊易位15例),臂间倒位6例,嵌合体1例;女性异常者29例,男性异常者9例。结论本文研究的资料说明染色体异常与自然流产关系密切,因此对无明显原因的自然流产夫妇应进行细胞遗传学检查。更多还原

【Abstract】 Objective To analyze the relation between abnormal karyotype and abnormal procreation.Methods The chromosomes of 593 couples with abnormal procreation were examined through cytogenetics methods.Results There were 38 chromosome aberrations(29 women,9 men) in them,the abnormal rate being 3.2%,including 31 balanced translocations(16 reciprocal translocations,15 Robertsonian translocations),6 pericentric inversions,and 1 mosaic.Conclusion This research indicates that chromosome aberration is related to spontaneous abortion closely,so the couples,among whom the wives have had spontaneous abortion,should be given chromosomes checking.更多还原