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正交试验优选冰片脂质体制备工艺的研究

Study on the Preparation Craft Selecting Liposome of Borneolum Syntheticum With Orthogonal Design

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【摘要】 目的 :研究冰片脂质体的最佳工艺。方法 :通过正交试验法 ,考察冰片的包封率这一指标。结果 :优选出试验因素 :磷脂量为 5 % (W /V) ,冰片与磷脂量之比为 1 10 (W/W ) ,胆固醇与磷脂量之比为 1 4 (W/W )。结论 :冰片采用水溶性药物分散法制备成脂质体可行

【Abstract】 Objective: To study the best craft produced liposome of borneolum syntheticum. Method: To investigate the envelopment rate of borneolum syntheticum by orthogonal design. Result: experimental factors :phospholipid was 5%, borneolum syntheticum : phospholipid was 110, cholesterin : phospholipid was 14. Conclusion: The method of water-soluble medicine disgregation was suitable for producing liposome with broneolum syntheticum.

【关键词】 冰片脂质体制备工艺
【Key words】 Broneolum syntheticumLiposomePreparation craft
  • 【分类号】TQ461
  • 【被引频次】7
  • 【下载频次】285
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