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无创双水平正压通气治疗急性左心衰的临床研究

Clinical Study of Noninvasive Bi-level Positive Airway Pressure Ventilation in the Treatment of Acute Left Heart Failure

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【作者】 孙孟彪王勤

【Author】 SUN Meng-biao, WANG Qin ( Department of Anesthesiology, Shenzhen Hospital, Peking University, Shenzhen 518035, China )

【机构】 北京大学深圳医院北京大学深圳医院 广东深圳518035广东深圳518035

【摘要】 【目的】观察无创双水平正压通气(BiPAP)在短期内治疗急性左心衰的临床疗效。【方法】58例急性左心衰患者随机分为两组,对照组28例,予常规吸氧治疗,BiPAP组30例,予BiPAP治疗。所有患者都同时接受常规抗心衰药物治疗。分别观察记录两组患者的临床表现及治疗前、后的血气(PaO2、PaCO2、SaO2)以及心率(HR)、呼吸频率(RR)等参数的变化,并作统计学分析。【结果】BiPAP组总有效率为93.3%,对照组总有效率为67.9%,两组比较差异有显著性(χ2=6.13,P<0.05)。与对照组比较,通气治疗后BiPAP组血气分析PaO2、PaCO2、SaO2各指标显著改善(P<0.05)。【结论】无创性BiPAP通气治疗急性左心衰能迅速改善患者的症状和低氧血症,是治疗急性左心衰的快速、有效的方法。

【Abstract】 [Objective]To assess the efficacy of noninvasive bi-level positive airway pressure (BiPAP) ventilation on acute left heart failure.[Methods]Fifty-eight patients with acute left heart failure were randomly divided into two groups. BiPAP group: 30 patients were treated by BiPAP ST-D30 accessory machines with traditional drugs. Control group: 28 patients were treated with traditional drugs alone. The changes of clinical symptoms and arterial blood gas indexes (PaO2、PaCO2、SaO2) were evaluated for the efficacy of BiPAP ventilation. [Results] The total efficiency rate of BiPAP group was 93.3%, while the total efficiency rate of control group was only 67.9%. After ventilation, arterial blood gas indexes (PaO2、PaCO2、SaO2) showed a statistical differences( P <0.05) between BiPAP group and control group.[Conclusion]Noninvasive BiPAP ventilation can improve symptoms and hypoxemia in patients with acute left heart failure. It is a feasible and effective method in treating acute left heart failure.

  • 【文献出处】 医学临床研究 ,Journal of Elinical Research , 编辑部邮箱 ,2005年06期
  • 【分类号】R541.6
  • 【被引频次】3
  • 【下载频次】44
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