【摘要】 【目的】探讨神经外科抗利尿激素分泌不当综合征(SIADH)的可能发生机制、诊断思路、鉴别诊断及抢救治疗方法。【方法】回顾分析 24 例 SIADH的临床诊治过程并进行文献复习。【结果】SIADH的特点为:①低血钠(血钠≤130 mmol/L);②低血渗(血浆渗透压≤270 mmol/L);③高尿钠(≥80 mmol/L);④中心静脉压正常或稍升高;⑤肾功能正常。【结论】在神经外科低钠血症的诊治过程中,在经过补充钠盐后仍有低钠血症者,应考虑SIADH存在的可能,需进一步明确诊断,SIADH与脑性盐耗综合征的鉴别非常重要。更多还原

【Abstract】 To study the mechanism, diagnosis, differential diagnosis and treatment for the syndrome of inappropriate antidiuretic hormone secretion(SIADH) in neurosurgery .Twenty-four cases of SIADH were analyzed retrospectively and the relevant literatures were reviewed.The characteristics of SIADH was ①hyponatremia(Na +≤130mmol/L ); ②hyposmolar syndrome(Posm≤270mosm/L);③natriuresis(Na +≥80 mmol/L) ;④CVP was normal;⑤function of kidney was normal.[Conclusion]SIADH often occurs in the neurosurgery patients, especially in the patients with hyponatremia. It is important to differentiate diagnosis SIADH from cerebral salt wasting syndrome(CSWS).更多还原