【摘要】 目的:了解女性生殖道解脲支原体(Uu)和人型支原体(Mh)的感染及药物敏感情况,为临床合理用药提供实验依据。方法:采用体外培养和药物敏感实验对1118例女性生殖道感染者的宫颈分泌物标本进行支原体感染及药物敏感性检测。结果:①有510例检测出支原体,阳性率为45.6%,其中Uu占33.5%,Mh占0.6%,Uu+Mh混合感染占11.5%;阳性患者主要分布于20～40岁年龄段,占41.7%(446/1118)。②Uu对交沙霉素(99.5%)、克拉霉素(96.0%)、强力霉素(95.2%)比较敏感,Uu+Mh对交沙霉素(84.4%)、强力霉素(84.4%)、美满霉素(80.5%)较敏感,Mh对交沙霉素(85.7%)、美满霉素(85.7%)、强力霉素(85.7%)较敏感。结论:①女性生殖道中支原体感染,以Uu感染为主,其次为Uu+Mh混合感染;女性支原体感染主要发生于性活跃期的育龄妇女。②支原体对常规抗生素已产生较高的耐药性率,治疗宜首选交沙霉素、强力霉素、美满霉素。更多还原

【Abstract】 Aim: To study the inflammation of ureaplasma urealyticum(Uu) and mycoplasma hominids(Mh)in the female genital duct and to analyze the drug sensitivities of the mycoplasma, so as to provide data for clinical reasonable use of medicine. Methods: Culture in vitro and drug sensitivity test were used in cerviced specimens from 1 118 female patients with genital inflammation. Results:There were 510 patients who had mycoplasma infection in the genital duct with a positive rate of 45.6%, among them 33.5% were infected by Uu and 0.6%, by Mh, and 11.5%,by Uu and Mh mixed. Most of the patients infected by mycoplasma were 20~40 years old(41.7%). The result of drug sensitivity test showed that Uu was more sensitive to jiaomycin(99.5%),cloriphromycin(96.0%),and doxycycline(95.2%), Uu+Mh to jiaomycin(84.4%), doxycycline(84.4%),minocycline(80.5%), and Mh to Jiaomycin(85.7%), minocycline(85.7%),and doxycycline(85.7%). Conclusion: Among mycoplasma infection in the female genital duct Uu takes the first place,and Uu+Mh, the second;the young women who have more sexual behaviors possesses the highest rate of mycoplasma infection;mycoplasma is resistant to many routine antibiotics.Josamycine, doxyclycline and minocycline are preferable for the treatment of mycoplasma infection.更多还原