【摘要】 目的分析鼻咽癌放疗致鼻窦炎发生的影响因素,探讨针对性干预措施,以降低其发生率。方法对66例鼻咽癌放射性鼻窦炎患者行回顾性多因素分析。结果鼻咽癌放疗后发生鼻窦炎与T分期高(P=0.003)、有无鼻腔侵犯(P=0.024)、有无鼻咽冲洗(P=0.000)显著相关;与患者的性别(P=0.5947)、淋巴转移与否(P=0.4548)、腔内后装治疗(P=0.8799)无关;用滴鼻剂者鼻窦炎发生率显著低于未用者(P<0.05)。结论T分期高和鼻腔受侵犯是客观危险因素,需早发现早治疗;鼻咽冲洗和应用滴鼻剂是主观保护因素,加强对鼻咽癌患者放疗全程鼻部护理,可降低鼻窦炎发生率。更多还原

【Abstract】 Objective To analyze the factors that affect the sinusitis of nasopharyngeal carcinoma (NPC) and explore the inte rvention measures to reduce the incidence of sinusitis. Methods The affecting factors of 66 nasopharyngeal cancer patients with radioactive sinu sitis were retrospectively analyzed. Results The main factors in volved in the development of radioactive sinusitis in the patients with nasopha ryngeal carcinoma included: later stage (P=0.003), invasion of nasal cavit y (P=0.024) and flushing of nasopharynx (P=0.000). It was not related to the sex ( P= 0.5947), lymph metastasis (P=0.4548) and afterloadin g brathytherapy (P=0.8799).Conclusion The later stage and in vasion of nasal cavity are objective risk factors which are difficult to control and can be prevented by early diagnosis and treatment. The local nursing, espec ially the flushing of nasal cavity has protective effect on the development of s inusitis. Intensive care of NPC patients during the whole course of radiotherapy can reduce the incidence of sinusitis.更多还原