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阿莫西林胶囊的制备及溶出度研究
Preparation and Dissolution of Amoxicillin Capsules
【摘要】 目的:提高阿莫西林的溶出度。方法:阿莫西林胶囊处方组成为每粒含阿莫西林0.25g,硬脂酸镁0.0075g,羧甲淀粉钠0.01g。结果:阿莫西林原粉溶出80%所需时间为65.37min,阿莫西林胶囊为20.56min。结论:本制备方法能明显提高其溶出度。
【Abstract】 Objective:Improve the dissolution of amoxicillin.Method:The formula of amoxicillin capsules was 0.25g amoxicillin,0.0075g magnesium stearate and 0.01g carboxymethylstach sodium in every capsule.Results:amoxicillin T80 =65.37min,amoxicillin capsules T80=20.56min.Conclusion:The method can improve the dissolution of amoxicillin.
- 【文献出处】 黑龙江医药 ,Heilongjiang Medical Journal , 编辑部邮箱 ,2005年04期
- 【分类号】TQ465.1
- 【被引频次】1
- 【下载频次】725