【摘要】 目的:了解中青年人群原发性高血压病患者早期干预治疗的预后。方法:选择动态血压增高而临床未确诊为高血压病(即临界高血压病)的中青年患者300例(观察组),另选280例动态血压正常者作对照(对照组)。将观察组分为药物治疗组、非治疗组、改变生活方式组三小组,分别给以不同的处理;三组患者均随访5年。结果:①观察组动态血压参数较对照组明显增高(P<0.05～<0.001)。②治疗后观察组三小组动态血压各参数比较,差异有显著性(P<0.01)。③随访结果:药物治疗组未见发展为明显的高血压病者和心脑血管事件者。非治疗组64例(68.1%)发展为明显的高血压,其中6例(6.4%)发生脑梗塞,2例(2.1%)发生脑出血,10例(10.6%)发生左心室肥厚。结论:动态血压监测在早期诊断高血压方面,有着明显的优势。早期高血压属于可逆性阶段,经积极治疗可以痊愈。更多还原

【Abstract】 Objective: To observe the prognosis of early intervention on essential hypertension in young to middle ages people.Method: 300 patients whose blood pressure were rising but no clinical diagnosis of hypertension were assigned as study group, 280 patients whose blood pressure were normal. The study group was randomly divided into three subgroups: treatment group, non-treatment group and change life style group. All subjects were followed-up five years.Result: The blood pressure indexes in the study group were significantly increased than that in the control group. After treatment, there were significantly statistic differences among three subgroups: no patients of treatment subgroup developed to typical hypertension and cardiocerebral events; 64 (68.1%)patients of non-treatment subgroup developing to typical hypertension, 6(6.4%) cases of them had cerebral infarction, 2(2.1%) cases of them had Cerebral hemorrhage, and 10(10.6%) cases of them had left ventricle. Conclusion: Ambulatory blood pressure monitoring has significantly superiority in the early diagnosis as hypertension.更多还原