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普鲁卡因和垂体后叶素对大咯血的疗效和副作用比较

Compare with the Effect and side Effect of Procaine and Pituitarii Posterioris in Treating Obvious Hemoptysis

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【作者】 陈江声杨燕娇翁锦文许永绥

【Author】 CHEN Jiang-sheng, YANG Yan -jiao, WENG Jin-wen, et al(The Second Affiliated Hospital of Shantou University Medical College, Guangdong Shantou 515041,China)

【机构】 汕头大学医学院第二附属医院汕头大学医学院第二附属医院 广东汕头515041广东汕头515041广东汕头515041

【摘要】 目的:比较垂体后叶素和普鲁卡因对大咯血的疗效及副作用。方法:64例大咯血的患者采用随机分配的方法,分别用普鲁卡因和垂体后叶素治疗。普鲁卡因组(34例):先用普鲁卡因100mg静脉推注,然后以60~120mg/h持续静脉滴注,出血停止后逐渐减量。对照组(30例):用垂体后叶素治疗,先用垂体后叶素5U静脉推注,然后以3-6U/h的速度持续静脉滴注,出血停止后逐渐减量。结果:普鲁卡因组34例病人中,治愈27例,占79.4%;失败7例,占20.6%。对照组30例中,治愈25例,占83.3%;失败5例,占16.7%。对照组的副作用发生率高达100%,治疗组为30%。两组间的治愈率和失败率的差别无统计学意义,P>0.05。两组间的副作用的差别有统计学意义,P<0.01。结论:普鲁卡因可安全而且有效用于大咯血的治疗。

【Abstract】 Objective: To compare with the effect and the side effect of procaine and pituitarii posterioris in treating obvious hemoptysis.Method:34 patients suffered from obvious hemoptysis were treated with procain, the control group were treated with pituitarii posterioris.Result:The curative rate of the group treated with procaine was 79.4%, the curative rate of the control group was 83.3%.The difference of two groups were no statistics significant,P>0.05. The side effect of two groups were significant, P<0.01. Conclusion:Procaine can be effective and safety used in treating obvious hemoptysis.

【关键词】 普鲁卡因垂体后叶素大咯血
【Key words】 ProcainePituitarii posteriorisHemoptysis
  • 【分类号】R56
  • 【被引频次】14
  • 【下载频次】90
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