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抗组胺新药非索非那定的合成和应用
Synthesis and Application of a New Antihistamine Drug--Fexofenadine
【摘要】 非索非那定是新一代的抗组胺药,用于治疗过敏性疾病,无镇静和嗜睡感,毒副作用小。综述了抗组胺新药 非索非那定的合成方法,比较了它们的优缺点,并对其应用前景作了展望。
【Abstract】 Fexofenadine is a new antihistamine drug used to treat anaphylaxis, and is not sedative and hypnotic. It has small poisoness and secondary reaction. In this paper, the synthetic methods of fexofenadine are reviewed, and their virtue and shortcoming are compared,and its applications are introduced and predicted.
【关键词】 抗组胺药;
H1受体拮抗剂;
非索非那定;
合成;
应用;
【Key words】 antihistamine drug; H1-histamine receptor antagonist; fexofenadine; synthesis; application;
【Key words】 antihistamine drug; H1-histamine receptor antagonist; fexofenadine; synthesis; application;
- 【文献出处】 化学与生物工程 , 编辑部邮箱 ,2005年11期
- 【分类号】R914.5
- 【被引频次】5
- 【下载频次】475